Covid y vitaminas

 Covid y altas dosis de IV vitamina C

1. Cheng, R. Video conference with Dr. ZY Peng, of the world's first high-dose IVC trial | Cheng Integrative Health Center Blog. https://www.drwlc.com/blog/2020/04/16/video-conference-with-dr-zy-peng-of-the-worlds-first-high-dose-ivc-trial/.

2. Cheng, R. Hospital treatment of serious and critical COVID-19 infection with high-dose Vitamin C | Cheng Integrative Health Center Blog. https://www.drwlc.com/blog/2020/03/18/hospital-treatment-of-serious-and-critical-covid-19-infection-with-high-dose-vitamin-c/.

3. NIH PDQ. High-Dose Vitamin C (PDQ(r))-Health Professional Version - National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq.

4. Cheng, R. Z. Can early and high intravenous dose of vitamin C prevent and treat coronavirus 2019 (COVID-19)? Medicine in Drug Discovery (2020).

5. Cheng, R. Covid-19 Presentations. drwlc.com https://www.drwlc.com/Covid-19_talks.shtml.

6. Cheng, R., Kogan, M. & Devra, D. Ascorbate as Prophylaxis and Therapy for COVID-19-Update From Shanghai and U.S. Medical Institutions - Richard Z Cheng, Mikhail Kogan, Devra Davis, 2020. https://journals.sagepub.com/doi/full/10.1177/2164956120934768.

7. Richard Z. Cheng. Protected Population Immunity, Not A Vaccine, Is The Way To Stop Covid-19 Pandemic. J Clin Immunol Immunother 6, 1-4 (2020).

8. Shanghai Government Officially Recommends Vitamin C for COVID-19. https://orthomolecular.org/resources/omns/v16n16.shtml.

9. Cheng, Richard. Shanghai and Guangdong Governements' official recommendation of Vit C in Covid-19 treatment. https://www.drwlc.com/blog/2020/04/16/covid-19-vitamin-c-and-integrative-medicine-3/.

10. Cheng, Richard. NIH Guest Speech: HDIVC on Covid-19. https://www.drwlc.com/Covid-19_talks.shtml.

11. Compassionate Drug Use. https://www.cancer.org/treatment/treatments-and-side-effects/clinical-trials/compassionate-drug-use.html.

Realidad

1. Saul AW (2020) Vitamin C Protects Against Coronavirus. Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n04.shtml

2. Front Line COVID-19 Critical Care Alliance: Prevention & Treatment Protocols for COVID-19. (2022) https://covid19criticalcare.com

3. Klenner FR. (1949) The treatment of poliomyelitis and other virus diseases with vitamin C. South Med J, 111:209-214. https://www.seanet.com/~alexs/ascorbate/194x/klenner-fr-southern_med_surg-1949-v111-n7-p209.htm

4. Klenner FR. (1951) Massive Doses of Vitamin C and the Virus Diseases. Presented in the Fifty-second Annual Meeting of the Tri-State Medical Association of the Carolinas and Virginia, held at Columbia, February 19th and 20th, 1951. https://www.seanet.com/~alexs/ascorbate/195x/klenner-fr-southern_med_surg-1951-v103-n4-p101.htm

5. Holford P, Carr AC, Zawari M, Vizcaychipi MP (2021) Vitamin C Intervention for Critical COVID-19: A Pragmatic Review of the Current Level of Evidence. Life, 11:1166. https://www.mdpi.com/2075-1729/11/11/1166

6. Holford P (2021) Twelve intervention trials conclude that vitamin C works for Covid. So why are hospitals being prohibited from using it? Orthomolecular Medicine News Service. https://www.orthomolecular.org/resources/omns/v17n27.shtml

7. Health Advisory and Recovery Team (2021) COVID-19: the case for supporting the human immune system with vitamin D: Why is this simple vitamin not promoted more? https://www.hartgroup.org/briefing-covid-19-the-case-for-supporting-the-human-immune-system-with-vitamin-d

8. Mohr SB, Gorham ED, Garland CF, et al. (2021) San Diego group studying positive effects of sunlight. https://pubmed.ncbi.nlm.nih.gov/?term=Mohr+SB+Gorham+ED+Garland+CF

9. Lowther M (2020) Why are there fewer nutrients in our food? Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n54.shtml

10. Downing D (2020) How we can fix this pandemic in a month. Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n49.shtml

11. Power ML, Oftedal OT, Savage A, et al. (1997) Assessing vitamin D status of callitrichids: Baseline data from wild cotton-top tamarins (Saguinus oedipus) in Colombia. Zoo Biol 16:39-46. https://doi.org/10.1002/(SICI)1098-2361(1997)16:1<39::AID-ZOO6>3.0.CO;2-C

12. Power ML, Dittus, WPJ (2017) Vitamin D status in wild toque macaques (Macaca sinica) in Sri Lanka. Am J Primatol. 79:e22655. https://www.primates.lk/health-vitamin-d-in-wild-monkeys-and-you

13. Vieth R (2006) Critique of the considerations for establishing the tolerable upper intake level for vitamin D: critical need for revision upwards. J Nutr, 136:1117-1122. https://pubmed.ncbi.nlm.nih.gov/16549491

1. The 10 deadliest epidemics throughout history. Health24. https://www.health24.com/medical/infectious-diseases/news/the-10-deadliest-epidemics-throughout-history-20170928.

2. The Most Dangerous Epidemics in U.S. History. Healthline. https://www.healthline.com/health/worst-disease-outbreaks-history.

3. List of Epidemics. Wikipedia. https://en.wikipedia.org/wiki/List_of_epidemics.

4. Fauci NEJM article about COVID-19: https://www.nejm.org/doi/full/10.1056/NEJMe2002387.

5. Fauci (2020) Dr. Fauci: You don't make the timeline, the virus does. (Endorses use of vit C, D) https://www.youtube.com/watch?v=xkyO1DTqoWQ&feature=youtu.be.

Vitamin C and COVID-19

6. Gage J (2020) New York hospitals giving patients 16 times the daily recommended dose of vitamin C to fight coronavirus. Washington Examiner, March 24, 2020 https://www.washingtonexaminer.com/news/new-york-hospitals-giving-patients-16-times-the-daily-recommended-dose-of-vitamin-c-to-fight-coronavirus.

7. Frieden T (2020) Former CDC Chief Dr. Tom Frieden: Coronavirus infection risk may be reduced by Vitamin D. https://www.foxnews.com/opinion/former-cdc-chief-tom-frieden-coronavirus-risk-may-be-reduced-with-vitamin-d.

8. Cheng R. (2020) Can early and large dose vitamin C be used in the treatment and prevention of COVID-19? Medicine Drug Discov. In Press, Journal Pre-proof. https://www.sciencedirect.com/science/article/pii/S2590098620300154.

9. Mongelli L, Golding B (2020) New York hospitals treating coronavirus patients with vitamin C. NY Post March 24, 2020 https://nypost.com/2020/03/24/new-york-hospitals-treating-coronavirus-patients-with-vitamin-c.

10. Cheng R (2020) NY Hospitals' use of Vit C is applaudable, but the dosage is too small. https://www.youtube.com/watch?v=NBbbncTR-3k.

11. Cheng R (2020) Shanghai Expert Consensus on COVID-19 Treatment, March 21, 2020. Shanghai Expert Group on Clinical Treatment of New Coronavirus Disease. Chinese Journal of Infectious Diseases, 2020, 38: Pre-published online. DOI: 10.3760 / cma.j.issn.1000-6680.2020.0016 https://www.drwlc.com/blog/2020/03/21/shanghai-expert-consensus-on-covid-19-treatment.

12. Cheng R (2020) Hospital treatment of serious and critical COVID-19 infection with high-dose Vitamin C. Posted on March 18, 2020 by Dr. Cheng. https://www.drwlc.com/blog/2020/03/18/hospital-treatment-of-serious-and-critical-covid-19-infection-with-high-dose-vitamin-c.

13. Lichtenstein K (2020) Can Vitamin C Prevent and Treat Coronavirus? MedicineNet on 03/09/2020. https://www.medicinenet.com/script/main/art.asp?articlekey=228745.

14. Hemilä H, Chalker E (2020) Vitamin C may reduce the duration of mechanical ventilation in critically ill patients: a meta-regression analysis. J Intensive Care 8:15. https://www.ncbi.nlm.nih.gov/pubmed/32047636.

15. Kashiouris MG, L'Heureux M, Cable CA, Fisher BJ, Leichtle SW, Fowler AA. (2020) The Emerging Role of Vitamin C as a Treatment for Sepsis. Nutrients. 12(2). pii: E292. https://www.ncbi.nlm.nih.gov/pubmed/31978969.

16. ZhiYong Peng, Zhongnan Hospital (2020) Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia. https://clinicaltrials.gov/ct2/show/NCT04264533.

17. Li J. (2018) Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis. Crit Care. 22:258. https://www.ncbi.nlm.nih.gov/pubmed/30305111.

18. Hemilä H, Louhiala P (2007) Vitamin C may affect lung infections. J Roy Soc Med. 100:495-498. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099400.

19. Cheng R (2020) Successful High-Dose Vitamin C Treatment of Patients with Serious and Critical COVID-19 Infection. Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n18.shtml.

20. Erol A. (2020) High-dose Intravenous Vitamin C Treatment for COVID-19. Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n19.shtml.

21. Player G, Saul AW, Downing D, Schuitemaker G. (2020) Published Research and Articles on Vitamin C as a Consideration for Pneumonia, Lung Infections, and the Novel Coronavirus (SARS-CoV-2/COVID-19) Orthomolecular Medicine News Service. https://orthomolecular.org/resources/omns/v16n20.shtml.

Vitamin C, on dosage

22. Gropper SS, Smith JL (2013) Advanced Nutrition and Human Metabolism, 6th Ed. Wadsworth, Cengage Learning. ISBN-13 9781133104056.

23. Cameron E, Pauling L. (1976) Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA. 73(10):3685-3689. https://www.ncbi.nlm.nih.gov/pubmed/1068480.

24. Cameron E, Pauling L. (1978) Supplemental ascorbate in the supportive treatment of cancer: reevaluation of prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA. 75:4538-4542. https://www.ncbi.nlm.nih.gov/pubmed/279931.

25. Carr AC, Cook J. (2018) Intravenous Vitamin C for Cancer Therapy - Identifying the Current Gaps in Our Knowledge. Front. Physiol. 9:1182. https://www.ncbi.nlm.nih.gov/pubmed/30190680.

26. Ried K, Travica N, Sali A (2016) The acute effect of high-dose intravenous vitamin C and other nutrients on blood pressure: a cohort study. Blood Press Monit. 21:160-167. https://www.ncbi.nlm.nih.gov/pubmed/26910646.

27. Hickey S, Roberts HJ, Cathcart RF, (2005) Dynamic Flow: A New Model for Ascorbate. J Orthomol Med. 20:237-244. https://orthomolecular.org/library/jom/2005/pdf/2005-v20n04-p237.pdf.

28. Cathcart RF (1981) The Method of Determining Proper Doses of Vitamin C for the Treatment of Disease byTitrating to Bowel Tolerance. J Orthomol Psychiat, 10:125-132. https://orthomolecular.org/library/jom/1981/pdf/1981-v10n02-p125.pdf

29. Levy TE (2011) Primal Panacea. Medfox Pub. ISBN-13: 978-0983772804.

30. Berger MM. (2009) Vitamin C Requirements in Parenteral Nutrition. Gastroenterology 137:S70-78. https://www.ncbi.nlm.nih.gov/pubmed/19874953.

31. Jalalzadeh M, Shekari E, Mirzamohammadi F, Ghadiani MH. (2012) Effect of short-term intravenous ascorbic acid on reducing ferritin in hemodialysis patients. Indian J Nephrol. 22:168-173. https://www.ncbi.nlm.nih.gov/pubmed/23087549.

Vitamin D

32. Grant WB, Giovannucci E. (2009) The possible roles of solar ultraviolet-B radiation and vitamin D in reducing case-fatality rates from the 1918-1919 influenza pandemic in the United States. Dermatoendocrinol. 1:215-219. https://www.ncbi.nlm.nih.gov/pubmed/20592793.

33. Dancer RC, Parekh D, Lax S, et al. (2015) Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax. 70:617-624. https://www.ncbi.nlm.nih.gov/pubmed/25903964.

34. McGreevey S, Morrison M. (2017) Study confirms vitamin D protects against colds and flu. Harvard Gazette, February 15, 2017. https://news.harvard.edu/gazette/story/2017/02/study-confirms-vitamin-d-protects-against-cold-and-flu.

35. Mamani M, Muceli N, Ghasemi Basir HR, Vasheghani M, Poorolajal J. (2017) Association between serum concentration of 25-hydroxyvitamin D and community-acquired| pneumonia: a case-control study. Int J Gen Med. 10:423-429. https://www.ncbi.nlm.nih.gov/pubmed/29180888.

36. Lu D, Zhang J, Ma C, Yue Y, et al (2018) Link between community-acquired pneumonia and vitamin D levels in older patients. Z Gerontol Geriatr. 51:435-439. https://www.ncbi.nlm.nih.gov/pubmed/28477055.

37. Slow S, Epton M, Storer M, et al. (2018) Effect of adjunctive single high-dose vitamin D3 on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Sci Rep. 2018 Sep 14;8:13829. https://www.ncbi.nlm.nih.gov/pubmed/30218062.

38. Brance ML, Miljevic JN, Tizziani R, Taberna ME, et al. (2018) Serum 25-hydroxyvitamin D levels in hospitalized adults with community-acquired| pneumonia. Clin Respir J. 12:2220-2227. https://www.ncbi.nlm.nih.gov/pubmed/29570946.

39. Zhou YF, Luo BA, Qin LL. (2019) The association between vitamin D deficiency and community-acquired pneumonia: A meta-analysis of observational studies. Medicine (Baltimore). 98(38):e17252. https://www.ncbi.nlm.nih.gov/pubmed/31567995.

40. Shirvani A, Kalajian TA, Song A, Holick MF. (2019) Disassociation of Vitamin D's Calcemic Activity and Non-calcemic Genomic Activity and Individual Responsiveness: A Randomized Controlled Double-Blind Clinical Trial. Sci Rep. 9(1):17685. https://www.ncbi.nlm.nih.gov/pubmed/31776371.

41. Gombart AF, Pierre A, Maggini S. (2020) A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 12(1). pii: E236. https://www.ncbi.nlm.nih.gov/pubmed/31963293.

42. Grant WB, Anouti FA, Moukayed M. (2020) Targeted 25-hydroxyvitamin D concentration measurements and vitamin D3 supplementation can have important patient and public health benefits Eur J Clin Nutrit. 74:366-376. https://doi.org/10.1038/s41430-020-0564-0.

43. Grant WB, Lahore H, McDonnell SL, et al. (2020) Evidence That Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Preprints 2020, 2020030235 https://www.preprints.org/manuscript/202003.0235/v2.

Other topics

44. Case HS (2017) Orthomolecular Nutrition for Everyone: Megavitamins and Your Best Health Ever. ISBN-13: 978-1681626574.

45. Prier M, Carr AC, Baillie N. (2018) No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study. Antioxidants (Basel). 7(5). pii: E68. https://www.ncbi.nlm.nih.gov/pubmed/29883396.

46. Dean C. The Magnesium Miracle. 2nd Ed., Ballantine Books, 2017, ISBN-13: 978-0399594441.

47. Levy TE (2019) Magnesium: Reversing Disease. Medfox Pub. ISBN-13: 978-0998312408

48. Saul AW. Glucose-6-phosphate dehydrogenase deficiency https://doctoryourself.com/G6PD.html. https://ghr.nlm.nih.gov/condition/glucose-6-phosphate-dehydrogenase-deficiency.

49. Harakeh S, Jariwalla RJ, Pauling L. (1990) Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells. Proc Natl Acad Sci USA. 87:7245-7249. https://www.pnas.org/content/87/18/7245.

50. Harakeh S, Jariwalla RJ. (1995) Ascorbate effect on cytokine stimulation of HIV production. Nutrition. 11:684-687. https://www.ncbi.nlm.nih.gov/pubmed/8748252.

Videos and audio on vitamin C:

Mary M, Ishaq S (2020a) Natural remedy could help the coronavirus. https://www.wdsu.com/article/a-natural-remedy-could-help-the-coronavirus/31935498.

Mary, M. (2020b) Vitamin C and other ways to possibly boost your immune system. https://www.wwltv.com/video/news/local/vitamin-c-and-other-ways-to-possibly-boost-your-immune-system/289-a23e152f-03e